Paul Capel Prize for young investigators in thrombosis research

About the Paul Capel Prize

Paul Capel, co-founder and first Secretary of the Belgian Society on Thrombosis and Haemostasis (BSTH), was the head of the coagulation laboratory at the ULB-Erasme Hospital and an expert in the field of Lupus Anticoagulant. He died unexpectedly in a car accident caused by a phantom driver. In his memory the BSTH instituted in 2000 the Paul Capel Prize for a young investigator for work presented as an oral communication at the BSTH annual meeting.

In 2009 the BSTH board decided to give out two Paul Capel Prizes each year, one in the category “Fundamental Research “ and one in the category “Clinical/Laboratory Research” to acknowledge the growing number of abstract submissions from clinicians and hospital laboratories.

Eline Hoes, Hasselt University

'Longitudinal Changes in Thrombin Generation Before and After Haemodialysis Initiation in Patients with End-Stage Kidney Disease'

Florence Putters, University of Liège

'Mechanistic study of the antivirulence activity of ticagrelor at antiplatelet dosage'

Andreas Verstraete, UZ Leuven

'Multi-Gene Panel for Thrombophilia Testing in Venous Thromboembolism'

Sofia F. Melo, University Of Liège, and Kato Ramaekers, KU Leuven

'Sustainable polymers with improved biocompatibility: new materials for blood-contacting medical devices', and 'imMKCL-based Glanzmann Thrombastenia models to study platelet formation and function'

Charlotte Van Edom, KU/UZ Leuven

'European practices on antithrombotic management during percutaneous mechanical circulatory support in adults: An international survey of the ACVC of the ESC joint with the EuroELSO'

Sarah Vandelanotte, KU Leuven Campus Kulak

'Analysis of the ultrastructural architecture of ischemic stroke thrombi using scanning electron microscopy: an observational study'

Severine De Bruijn, UZA

'First report of a de novo iTTP episode associated with an mRNA-based anti-COVID-19 vaccination'

Severien Meyers, KU Leuven

'Neutrophils promote the progression of Staphylococcus aureus endocarditis'

Christophe Vandenbriele, UZ Leuven

'Optimal antithrombotic regimen in patients with cardiogenic shock on ImpellaTM mechanical support: less might be more'

Shannen Deconinck, KU Leuven campus Kulak, and Coraline Radermecker, GIGA Institute, Liege University

'Inhibition of ADAMTS13 rescues acquired von Willebrand syndrome in a preclinical mechanical circulatory support animal model' and 'Neutrophil extracellular traps infiltrate the lung airway, interstitial, and vascular compartments in severe COVID-19'

Senna Staessens, KU Leuven campus Kulak

'Histological analysis of a thrombectomy-resistant ischemic stroke thrombus: a case report'

Joachim Mertens, UZA

'Evaluation of the time course of Carboxypeptidase U (CPU, CPB2, TAFIa) generation and influence of AZD9684, a selective CPU inhibitor, in experimental rat stroke models.'

Senna Staessens, KU Leuven campus Kulak

'Platelet-rich but not RBC-rich areas in stroke thrombi consist of dense fibrin structures, VWF and extracellular DNA'

Severien Meyers, KU Leuven

'The differential role of platelets and fibrin in adhesion on inflamed and damaged valves in a new mouse model of early staphylococcus aureus endocarditis'

Shakeel Kautbally, UC Louvain

'Increased Acetyl-CoA carbox ylase phosphorylation I state in platelets identify high risk patients with coronary artery disease: ACCTHEROMA trial '

An-Sofie Schelpe, KU Leuven Campus Kulak

'Unraveling anti-spacer immunoprofiles of acquired TTP patients using anti-idiotypic antibodies'

An-Sofie Schelpe, KU Leuven Campus Kulak

'The p.Arg498Cys mutation in the cysteine rich domain of ADAMTS13 results in a secretion deficiency'

Laurens Liesenborghs, KU Leuven

'Staphylococcus aureus and Staphylococcus lugdunensis bind von Willebrand Factor to overcome shear stress and cause endocarditis'

Frederik Denorme KU Leuven Campus Kulak, and Marijke Peetermans, KU Leuven

'The role of ADAMTS13 and VWF in Patients with Acute Ischemic Stroke: a Case Control Study', and 'Addition of idarucizumab to plasma samples containing dabigatran allows to use routine coagulation assays to diagnose hemostasis disorders'

Christophe Vandenbriele KU Leuven, and Frederik Denorme KU Leuven Campus Kulak

'Platelet Endothelial Aggregation Receptor 1: a novel modifier of neo-angiogenesis' and 'the prothrombolytic effect of ADAMTS13 in a mouse model of stroke'

An De Vriese, AZ Brugge / OLV Aalst, and Christophe Vandenbriele, KU Leuven

'Dose finding of Rivaroxaban in hemodialysis patients', and ' Rivaroxaban for the treatment of consumptive coagulopathy associated with vascular malformations'

Sebastien Verhenne, KU Leuven Campus Kulak

'Sleeping Beauty’-mediated gene transfer of ADAMTS13 prevents the onset of TTP-like symptoms in ADAMTS13-deficient mice'

Elien De Cock KU Leuven Campus Kulak, shared with Lize Bollen, KU Leuven

Xiaohua Zhou, KU Leuven

'Generation of a deletion mutant of TAFI with a 100-fold increased intrinsic catalytic activity'

Inge Vangknechten, UZA

'the Belgian-Czech cooperation in the BRNO-Von Willebrand Study: an update'.

Thomas Vanassche, KU Leuven

'The misuse of the host coagulation system by S.aureus: a potential novel target for treatment?'